PUM2 anticorps (N-Term)

N° du produit ABIN2779082

Détail du produit anti-PUM2 anticorps

Antigène: PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Lapin, Boeuf (Vache), Porc, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PUM2 est non-conjugé

Application: Western Blotting (WB)

Séquence: SSPADKLDSR FRKGNFGTRD AETDGPEKGD QKGKASPFEE DQNRDLKQGD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PUM2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PUM2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1064 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PUM2 (ABIN2779082)

Hynes, Calder, Rosenfeld, Scott: "The use of tranexamic acid to reduce blood loss during total hip arthroplasty: an observational study." dans: Annals of the Royal College of Surgeons of England, Vol. 87, Issue 2, pp. 99-101, (2005) (PubMed).

Détails sur PUM2

Antigène: PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))

Autre désignation: PUM2 (PUM2 Produits)

Synonymes: anticorps pum-2, anticorps 5730503J23Rik, anticorps Pumm2, anticorps mKIAA0235, anticorps PUMH2, anticorps PUML2, anticorps pumilio RNA binding family member 2, anticorps pumilio RNA-binding family member 2, anticorps pum2, anticorps Pum2, anticorps PUM2

Sujet: PUM2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.
Alias Symbols: KIAA0235, PUMH2, PUML2
Protein Interaction Partner: NANOS3, BMI1, gag-pol, UBC, DAZL, DAZ1, ELAVL1, MED4, AURKA, NANOS1, DAZ2, DAZ4, PUM2, MED23, IKZF5,
Protein Size: 1064

Poids moléculaire: 117 kDa

ID gène: 23369

NCBI Accession: NM_015317, NP_056132

Pathways: Ribonucleoprotein Complex Subunit Organization