MXD3 anticorps (N-Term)

N° du produit ABIN2779271

Détail du produit anti-MXD3 anticorps

Antigène: MXD3 (MAX Dimerization Protein 3 (MXD3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MXD3 est non-conjugé

Application: Western Blotting (WB)

Séquence: PIHRRKKRPP QAPGAQDSGR SVHNELEKRR RAQLKRCLER LKQQMPLGAD

Homologie: Cow: 93%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 86%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MXD3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MXD3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 206 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-MXD3 (ABIN2779271)

Suzuki, Yoshitomo-Nakagawa, Maruyama, Suyama, Sugano: "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." dans: Gene, Vol. 200, Issue 1-2, pp. 149-56, (1997) (PubMed).

Détails sur MXD3

Antigène: MXD3 (MAX Dimerization Protein 3 (MXD3))

Autre désignation: MXD3 (MXD3 Produits)

Synonymes: anticorps Mad3, anticorps BHLHC13, anticorps MAD3, anticorps MYX, anticorps 4631412E13Rik, anticorps bHLHc13, anticorps Mad, anticorps zgc:66281, anticorps Myx, anticorps MAX dimerization protein 3, anticorps Max dimerization protein 3, anticorps MAX dimerization protein 3 L homeolog, anticorps mxd3, anticorps MXD3, anticorps Mxd3, anticorps mxd3.L

Sujet: MXD3 contains 1 basic helix-loop-helix (bHLH) domain. It is a transcriptional repressor and binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
Alias Symbols: MYX, MAD3, BHLHC13
Protein Interaction Partner: NOTCH2NL, KRTAP10-7, UBC, NFKB1, MAGEA11, MAX, SIN3A, SMC3,
Protein Size: 206

Poids moléculaire: 23 kDa

ID gène: 83463

NCBI Accession: NM_031300, NP_112590

UniProt: Q9BW11