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TCF7L1 anticorps (N-Term)

TCF7L1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2779272
  • Antigène Voir toutes TCF7L1 Anticorps
    TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))
    Épitope
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 33
    • 16
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye
    Hôte
    • 31
    • 1
    • 1
    Lapin
    Clonalité
    • 33
    Polyclonal
    Conjugué
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp TCF7L1 est non-conjugé
    Application
    • 17
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    NDELIPFQDE GGEEQEPSSD SASAQRDLDE VKSSLVNESE NQSSSSDSEA
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against TCF7L1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human TCF7L1
    Top Product
    Discover our top product TCF7L1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 588 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))
    Autre désignation
    TCF7L1 (TCF7L1 Produits)
    Synonymes
    anticorps TCF-3, anticorps TCF3, anticorps Tcf-3, anticorps Tcf3, anticorps bHLHb21, anticorps tcf3c, anticorps tcf3d, anticorps xtcf3, anticorps XTCF-3, anticorps tcf7l1, anticorps tcf3b, anticorps TCF-3-A, anticorps tcf-3, anticorps tcf3, anticorps tcf3a, anticorps zTcf-3, anticorps transcription factor 7 like 1, anticorps transcription factor 7 like 1 (T cell specific, HMG box), anticorps transcription factor 7 like 1 L homeolog, anticorps transcription factor 7 like 1 S homeolog, anticorps transcription factor 7 like 1b, anticorps transcription factor 7 like 1a, anticorps TCF7L1, anticorps Tcf7l1, anticorps tcf7l1.L, anticorps tcf7l1.S, anticorps tcf7l1b, anticorps tcf7l1a
    Sujet
    TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
    Alias Symbols: TCF-3, TCF3
    Protein Interaction Partner: UBC, mdfic, Mdfi, DAZAP2, CTNNB1,
    Protein Size: 588
    Poids moléculaire
    63 kDa
    ID gène
    83439
    NCBI Accession
    NM_031283, NP_112573
    UniProt
    Q9HCS4
    Pathways
    Signalisation WNT, Stem Cell Maintenance
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