Crk anticorps (C-Term)
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- Antigène Voir toutes Crk (CRK) Anticorps
- Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Crk est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- IPVPYVEKYR PASASVSALI GGNQEGSHPQ PLGGPEPGPY AQPSVNTPLP
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against CRK. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product CRK Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 304 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
- Autre désignation
- CRK (CRK Produits)
- Synonymes
- anticorps CG1587, anticorps CRK, anticorps D-CRK, anticorps D-Crk, anticorps DCrk, anticorps Dcrk, anticorps Dmel\\CG1587, anticorps crk, anticorps dCRK, anticorps dCrk, anticorps fb34h10, anticorps fc05a01, anticorps fi19g05, anticorps wu:fb34h10, anticorps wu:fc05a01, anticorps wu:fc54a04, anticorps wu:fi19g05, anticorps zgc:100936, anticorps CRKII, anticorps p38, anticorps Crko, anticorps crk2, anticorps crkII, anticorps v-crk, anticorps P38C-CRK, anticorps Crk-I, anticorps Crk-II, anticorps Crk-III, anticorps Crk3, anticorps CrkIII, anticorps c-Crk, anticorps Crk oncogene, anticorps v-crk avian sarcoma virus CT10 oncogene homolog, anticorps CRK proto-oncogene, adaptor protein, anticorps v-crk avian sarcoma virus CT10 oncogene homolog L homeolog, anticorps v-crk sarcoma virus CT10 oncogene homolog, anticorps Crk, anticorps crk, anticorps CRK, anticorps crk.L
- Sujet
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This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
Alias Symbols: CRKII, p38
Protein Interaction Partner: FAM154A, HUWE1, ABL2, ABL1, SPRR2A, MET, CBL, BAG3, LMNA, ERBB3, ERBB2, EGFR, PPFIBP2, ATXN1, PTPN4, MAPK4, DOK1, BCAR1, NANS, FUBP1, SPR, HSPB1, DHX9, SERPINH1, ATIC, PIK3R2, PIK3R1, PIK3CD, PIK3CB, PIK3CA, PIK3C2B, SERPINB6, LYZ, KRT19, KRT17, KRT16, KR
Protein Size: 304 - Poids moléculaire
- 34 kDa
- ID gène
- 1398
- NCBI Accession
- NM_016823, NP_058431
- UniProt
- P46108
- Pathways
- Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
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