CLK4 anticorps (N-Term)

N° du produit ABIN2779361

Détail du produit anti-CLK4 anticorps

Antigène: CLK4 (CDC-Like Kinase 4 (CLK4))

Épitope: N-Term

Reactivité: Souris, Humain, Lapin, Chien, Cobaye, Boeuf (Vache), Cheval, Rat, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLK4 est non-conjugé

Application: Western Blotting (WB)

Séquence: RSRRSSPKRK RNRHCSSHQS RSKSHRRKRS RSIEDDEEGH LICQSGDVLR

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 91%

Attributs du produit: This is a rabbit polyclonal antibody against CLK4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CLK4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 481 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CLK4 (ABIN2779361)

Eisenreich, Zakrzewicz, Huber, Thierbach, Pepke, Goldin-Lang, Schultheiss, Pries, Rauch: "Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells." dans: Oncology reports, Vol. 30, Issue 1, pp. 462-70, (2013) (PubMed).

Détails sur CLK4

Antigène: CLK4 (CDC-Like Kinase 4 (CLK4))

Autre désignation: CLK4 (CLK4 Produits)

Synonymes: anticorps AI987988, anticorps C85119, anticorps zgc:112975, anticorps CDC like kinase 4, anticorps CDC-like kinase 4, anticorps CDC-like kinase 4b, anticorps CLK4, anticorps Clk4, anticorps clk4b

Sujet: The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.
Alias Symbols: DKFZp686A20267
Protein Interaction Partner: KPNA1, KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, CLK4, SRRM2, AHCYL2, SUB1, RASA4, SRPK1, RNF181, CLASRP, UBL5, HSPB2,
Protein Size: 481

Poids moléculaire: 57 kDa

ID gène: 57396

NCBI Accession: NM_020666, NP_065717

UniProt: Q9HAZ1