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CLK4 anticorps (N-Term)

CLK4 Reactivité: Souris, Humain, Lapin, Chien, Cobaye, Boeuf (Vache), Cheval, Rat, Saccharomyces cerevisiae WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2779361
  • Antigène Voir toutes CLK4 Anticorps
    CLK4 (CDC-Like Kinase 4 (CLK4))
    Épitope
    • 9
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 30
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Souris, Humain, Lapin, Chien, Cobaye, Boeuf (Vache), Cheval, Rat, Saccharomyces cerevisiae
    Hôte
    • 31
    • 1
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CLK4 est non-conjugé
    Application
    • 25
    • 19
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    RSRRSSPKRK RNRHCSSHQS RSKSHRRKRS RSIEDDEEGH LICQSGDVLR
    Homologie
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 91%
    Attributs du produit
    This is a rabbit polyclonal antibody against CLK4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human CLK4
    Top Product
    Discover our top product CLK4 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 481 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Eisenreich, Zakrzewicz, Huber, Thierbach, Pepke, Goldin-Lang, Schultheiss, Pries, Rauch: "Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells." dans: Oncology reports, Vol. 30, Issue 1, pp. 462-70, (2013) (PubMed).

  • Antigène
    CLK4 (CDC-Like Kinase 4 (CLK4))
    Autre désignation
    CLK4 (CLK4 Produits)
    Synonymes
    anticorps AI987988, anticorps C85119, anticorps zgc:112975, anticorps CDC like kinase 4, anticorps CDC-like kinase 4, anticorps CDC-like kinase 4b, anticorps CLK4, anticorps Clk4, anticorps clk4b
    Sujet
    The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.
    Alias Symbols: DKFZp686A20267
    Protein Interaction Partner: KPNA1, KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, CLK4, SRRM2, AHCYL2, SUB1, RASA4, SRPK1, RNF181, CLASRP, UBL5, HSPB2,
    Protein Size: 481
    Poids moléculaire
    57 kDa
    ID gène
    57396
    NCBI Accession
    NM_020666, NP_065717
    UniProt
    Q9HAZ1
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