DYRK3 anticorps (N-Term)

N° du produit ABIN2779364

Détail du produit anti-DYRK3 anticorps

Antigène: DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DYRK3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: GDHTQHFLDG GEMKVEQLFQ EFGNRKSNTI QSDGISDSEK CSPTVSQGKS

Homologie: Human: 100%, Mouse: 86%

Attributs du produit: This is a rabbit polyclonal antibody against DYRK3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DYRK3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 588 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DYRK3 (ABIN2779364)

Wippich, Bodenmiller, Trajkovska, Wanka, Aebersold, Pelkmans: "Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling." dans: Cell, Vol. 152, Issue 4, pp. 791-805, (2013) (PubMed).

Détails sur DYRK3

Antigène: DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))

Autre désignation: DYRK3 (DYRK3 Produits)

Synonymes: anticorps DYRK5, anticorps RED, anticorps REDK, anticorps hYAK3-2, anticorps BC006704, anticorps DYRK3, anticorps MGC89944, anticorps dual specificity tyrosine phosphorylation regulated kinase 3, anticorps dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3, anticorps dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3, anticorps dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3 L homeolog, anticorps DYRK3, anticorps Dyrk3, anticorps dyrk3, anticorps dyrk3.L

Sujet: This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: DYRK5, RED, REDK, hYAK3-2
Protein Interaction Partner: DYRK3, SORL1, FBXO25, PRNP, NEDD4L,
Protein Size: 588

Poids moléculaire: 66 kDa

ID gène: 8444

NCBI Accession: NM_003582, NP_003573

UniProt: O43781

Pathways: Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha