Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

DYRK3 anticorps (N-Term)

DYRK3 Reactivité: Humain, Souris WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2779364
  • Antigène Voir toutes DYRK3 Anticorps
    DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))
    Épitope
    • 15
    • 9
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 51
    • 34
    • 21
    • 1
    • 1
    Humain, Souris
    Hôte
    • 63
    • 3
    • 1
    Lapin
    Clonalité
    • 64
    • 3
    Polyclonal
    Conjugué
    • 25
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp DYRK3 est non-conjugé
    Application
    • 59
    • 26
    • 25
    • 13
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Séquence
    GDHTQHFLDG GEMKVEQLFQ EFGNRKSNTI QSDGISDSEK CSPTVSQGKS
    Homologie
    Human: 100%, Mouse: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against DYRK3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human DYRK3
    Top Product
    Discover our top product DYRK3 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 588 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wippich, Bodenmiller, Trajkovska, Wanka, Aebersold, Pelkmans: "Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling." dans: Cell, Vol. 152, Issue 4, pp. 791-805, (2013) (PubMed).

  • Antigène
    DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))
    Autre désignation
    DYRK3 (DYRK3 Produits)
    Synonymes
    anticorps DYRK5, anticorps RED, anticorps REDK, anticorps hYAK3-2, anticorps BC006704, anticorps DYRK3, anticorps MGC89944, anticorps dual specificity tyrosine phosphorylation regulated kinase 3, anticorps dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3, anticorps dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3, anticorps dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3 L homeolog, anticorps DYRK3, anticorps Dyrk3, anticorps dyrk3, anticorps dyrk3.L
    Sujet
    This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Alias Symbols: DYRK5, RED, REDK, hYAK3-2
    Protein Interaction Partner: DYRK3, SORL1, FBXO25, PRNP, NEDD4L,
    Protein Size: 588
    Poids moléculaire
    66 kDa
    ID gène
    8444
    NCBI Accession
    NM_003582, NP_003573
    UniProt
    O43781
    Pathways
    Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
Vous êtes ici:
Support technique