CCBP2 anticorps (N-Term)

N° du produit ABIN2779383

Détail du produit anti-CCBP2 anticorps

Antigène: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Épitope: N-Term

Reactivité: Humain, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCBP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MAATASPQPL ATEDADSENS SFYYYDYLDE VAFMLCRKDA VVSFGKVFLP

Homologie: Human: 100%, Rabbit: 86%

Attributs du produit: This is a rabbit polyclonal antibody against CCBP2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CCBP2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 384 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CCBP2

Antigène: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Autre désignation: CCBP2 (CCBP2 Produits)

Sujet: CCBP2 is a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown.This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.
Alias Symbols: CCR10, CCR9, CMKBR9, D6, MGC126678, MGC138250, hD6, CCBP2
Protein Interaction Partner: APP, CCL3L3, CCL28, CCL27, CCL21, CCL25, CCL8, CCL19, CCL14, CCL13, CCL11, CCL5, CCL4, CCL3, CCL7, CCL2,
Protein Size: 384

Poids moléculaire: 43 kDa

ID gène: 1238

NCBI Accession: NM_001296, NP_001287

UniProt: O00590