CXCR4 anticorps (N-Term)
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- Antigène Voir toutes CXCR4 Anticorps
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Lapin, Porc, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CXCR4 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Séquence
- MEGISIYTSD NYTEEMGSGD YDSMKEPCFR EENANFNKIF LPTIYSIIFL
- Homologie
- Horse: 89%, Human: 91%, Mouse: 77%, Pig: 91%, Rabbit: 85%, Rat: 77%
- Attributs du produit
- This is a rabbit polyclonal antibody against CXCR4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CXCR4
- Top Product
- Discover our top product CXCR4 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 352 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- Autre désignation
- CXCR4 (CXCR4 Produits)
- Sujet
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CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
Protein Interaction Partner: UBC, ITCH, nef, P4HB, CD4, env, MYBL2, ST13, ATP13A2, CXCL12, PTPN11, STAM, CAV1, SUMO4, HLA-C, SDC4, HSPA8, GNA13, STAT5B, SOCS3, SOCS1, CCR5, PTK2, STAT2, STAT1, JAK3, DPP4, PTPN6, VAV1, CXCR4, MYH9, PTPRC, JAK2, JAK1, GNAI1, ELANE, CTSG, ADRBK2, ARRB2,
Protein Size: 352 - Poids moléculaire
- 40 kDa
- ID gène
- 7852
- NCBI Accession
- NM_003467, NP_003458
- UniProt
- P61073
- Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events
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