SMAD5 anticorps (Middle Region)

N° du produit ABIN2779414

Détail du produit anti-SMAD5 anticorps

Antigène: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Mouton, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD5 est non-conjugé

Application: Western Blotting (WB)

Séquence: YPPSPASSTY PNSPASSGPG SPFQLPADTP PPAYMPPDDQ MGQDNSQPMD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SMAD5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SMAD5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 465 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SMAD5

Antigène: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Autre désignation: SMAD5 (SMAD5 Produits)

Synonymes: anticorps DWFC, anticorps JV5-1, anticorps MADH5, anticorps Madh5, anticorps SBN, anticorps fb67b04, anticorps mad, anticorps madh5, anticorps sb:cb400, anticorps smd5, anticorps wu:fb67b04, anticorps SMAD5, anticorps DKFZp468M0619, anticorps 1110051M15Rik, anticorps AI451355, anticorps Dwf-C, anticorps MusMLP, anticorps SMAD family member 5, anticorps SMAD5, anticorps Smad5, anticorps smad5

Sujet: SMAD5 undergoes copy number gain and increased expression, rather than loss of expression, and therefore does not act as a tumor-suppressor gene in hepatocellular carcinoma. Up-regulated Smad5 mediates apoptosis of gastric epithelial cells induced by Helicobacter pylori infection.
Alias Symbols: DWFC, JV5-1, MADH5
Protein Interaction Partner: UBC, SUMO1, HECW2, HBG2, BCAT1, SOX5, SNRPA, SNRNP70, SFPQ, RYR2, RBM4, PTPN12, PSMD11, NEDD4, SMAD4, SMAD1, ANKRD13A, PPIL4, SOX7, SMURF2, SMURF1, MTMR10, CHMP3, CXXC5, SF3B1, U2AF2, PNKP, WWP1, NAA20, EPN1, SMAD3, SMAD2, PAX6, COPS5, HGS, EP300, ELAVL1,
Protein Size: 465

Poids moléculaire: 51 kDa

ID gène: 4090

NCBI Accession: NM_005903, NP_005894

UniProt: Q99717