MTF1 anticorps (C-Term)
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- Antigène Voir toutes MTF1 Anticorps
- MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))
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Épitope
- C-Term
- Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MTF1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- QSSLVMGEQN LQWILNGATS SPQNQEQIQQ ASKVEKVFFT TAVPVASSPG
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against MTF1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human MTF1
- Top Product
- Discover our top product MTF1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 753 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))
- Autre désignation
- MTF1 (MTF1 Produits)
- Synonymes
- anticorps MTF-1, anticorps MTF1, anticorps mtf1, anticorps MGC86485, anticorps Thyls, anticorps ZRF, anticorps metal regulatory transcription factor 1, anticorps metal-regulatory transcription factor 1, anticorps metal-regulatory transcription factor 1 L homeolog, anticorps metal response element binding transcription factor 1, anticorps MTF1, anticorps mtf1, anticorps mtf1.L, anticorps Mtf1
- Sujet
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The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein.
Alias Symbols: ZRF, MTF-1
Protein Interaction Partner: AP1M1, EP300, CREBBP, MT1G,
Protein Size: 753 - Poids moléculaire
- 81 kDa
- ID gène
- 4520
- NCBI Accession
- NM_005955, NP_005946
- UniProt
- Q14872
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