NFKB2 anticorps (C-Term)
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- Antigène Voir toutes NFKB2 Anticorps
- NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Boeuf (Vache), Porc, Lapin, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NFKB2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- SDSDSDSEGP EKDTRSSFRG HTPLDLTCST LVKTLLLNAA QNTMEPPL
- Homologie
- Cow: 77%, Horse: 85%, Human: 100%, Pig: 77%, Rabbit: 92%, Rat: 77%
- Attributs du produit
- This is a rabbit polyclonal antibody against NFKB2. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human NFKB2
- Top Product
- Discover our top product NFKB2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 933 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Characterization of a negative feedback network between SUMO4 expression and NFkappaB transcriptional activity." dans: Biochemical and biophysical research communications, Vol. 381, Issue 4, pp. 477-81, (2009) (PubMed).
: "Distinctive expression of chemokines and transforming growth factor-beta signaling in human arterial endothelium during atherosclerosis." dans: The American journal of pathology, Vol. 171, Issue 1, pp. 326-37, (2007) (PubMed).
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Characterization of a negative feedback network between SUMO4 expression and NFkappaB transcriptional activity." dans: Biochemical and biophysical research communications, Vol. 381, Issue 4, pp. 477-81, (2009) (PubMed).
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- Antigène
- NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
- Autre désignation
- NFKB2 (NFKB2 Produits)
- Synonymes
- anticorps NF-kappaB2, anticorps lyt, anticorps p49, anticorps p49/p100, anticorps p50B, anticorps p52, anticorps nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100, anticorps Nfkb2
- Sujet
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NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
Alias Symbols: p52, H2TF1, LYT10, LYT-10
Protein Interaction Partner: FBXW11, UBC, RELB, RELA, REL, NFKB1, CHUK, BCL3, SUMO1, NEDD8, TNFAIP3, BIRC2, EPS8, VCP, UBD, BRRF1, COMMD1, COMMD2, MAP3K14, BTRC, NFKB2, FBXW7, TSG101, IKBKG, SUMO2, DPF2, PSMD11, NFKBIZ, TNIP2, HDAC5, NFKBIB, HDAC4, USP2, NFKBIE, RPL6, IKBKB, TSC22D3,
Protein Size: 900 - Poids moléculaire
- 97 kDa
- ID gène
- 4791
- NCBI Accession
- NM_002502, NP_002493
- UniProt
- Q00653
- Pathways
- Toll-Like Receptors Cascades
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