WNT1 anticorps (C-Term)
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- Antigène Voir toutes WNT1 Anticorps
- WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cheval, Cobaye, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp WNT1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- NFCTYSGRLG TAGTAGRACN SSSPALDGCE LLCCGRGHRT RTQRVTERCN
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against Wnt1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of MOUSE Wnt1
- Top Product
- Discover our top product WNT1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
- Autre désignation
- Wnt1 (WNT1 Produits)
- Synonymes
- anticorps Xint-1, anticorps Xwnt1, anticorps int-1, anticorps int1, anticorps wnt-1, anticorps wnt1-a, anticorps Int-1, anticorps Wnt-1, anticorps sw, anticorps swaying, anticorps BMND16, anticorps INT1, anticorps OI15, anticorps Int1, anticorps WNT-1, anticorps sb:eu647, anticorps zgc:194464, anticorps zgc:194478, anticorps WNT1, anticorps Wnt family member 1, anticorps Wnt family member 1 L homeolog, anticorps wingless-type MMTV integration site family, member 1, anticorps WNT1, anticorps wnt1.L, anticorps Wnt1, anticorps wnt1
- Sujet
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Wnt1 is a ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, it is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. It is a probable developmental protein and may be a signaling molecule important in CNS development. Wnt1 is likely to signal over only few cell diameters. It ha s a proeminent role in the induction of the mesencephalon and cerebellum. It may play a crucial role in the morphogenesis of the neural tube and/or the early stages of CNS development. It has a role in osteoblast function and bone development.
Alias Symbols: Int-1, Wnt-1, sw, swaying
Protein Interaction Partner: lrp6-b, Lrp6, Wnt3a, Porcn, Ryk, Lrp5, Fzd8, Fzd1, Dkk1,
Protein Size: 370 - Poids moléculaire
- 40 kDa
- ID gène
- 22408
- NCBI Accession
- NM_021279, NP_067254
- UniProt
- P04426
- Pathways
- Signalisation WNT, Dopaminergic Neurogenesis
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