TAF11 anticorps (N-Term)

N° du produit ABIN2779473

Détail du produit anti-TAF11 anticorps

Antigène: TAF11 (TATA Box Binding Protein Associated Factor 11 (TAF11))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAF11 est non-conjugé

Application: Western Blotting (WB)

Séquence: MDDAHESPSD KGGETGESDE TAAVPGDPGA TDTDGIPEET DGDADVDLKE

Homologie: Cow: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 83%, Rabbit: 92%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TAF11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TAF11

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 211 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TAF11 (ABIN2779473)

Anish, Hossain, Jacobson, Takada: "Characterization of transcription from TATA-less promoters: identification of a new core promoter element XCPE2 and analysis of factor requirements." dans: PLoS ONE, Vol. 4, Issue 4, pp. e5103, (2009) (PubMed).

Détails sur TAF11

Antigène: TAF11 (TATA Box Binding Protein Associated Factor 11 (TAF11))

Autre désignation: TAF11 (TAF11 Produits)

Synonymes: anticorps 1110038O14Rik, anticorps 28kDa, anticorps AI115401, anticorps AL024207, anticorps AW552398, anticorps PRO214, anticorps TAF2I, anticorps TAFII28, anticorps MGC:15243, anticorps TATA-box binding protein associated factor 11, anticorps Taf11, anticorps TAF11

Sujet: TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF11 is a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.
Alias Symbols: TAF2I, PRO2134, TAFII28, MGC:15243
Protein Interaction Partner: APPBP2, MED26, HIST3H3, APP, TBP, ELAVL1, POLR2A, ACTB, TAF8, VDR, THRA, NFYC, NFYB, NFYA, LZTR1, TAF9, TAF12, TAF10, TAF5, TAF13, TAF6, TAF4, TAF7, TAF2, CPSF1, TRIM24, TAF1, RXRB, RXRA, RELA, TAF15, GTF2F1, GTF2E1, GTF2B,
Protein Size: 211

Poids moléculaire: 23 kDa

ID gène: 6882

NCBI Accession: NM_005643, NP_005634

UniProt: Q15544