SPIC anticorps (C-Term)

N° du produit ABIN2779513

Détail du produit anti-SPIC anticorps

Antigène: SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

Épitope: C-Term

Reactivité: Humain, Souris, Boeuf (Vache), Cheval, Chien, Cobaye, Rat, Lapin, Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPIC est non-conjugé

Application: Western Blotting (WB)

Séquence: EKLAELWGKR KGNRKTMTYQ KMARALRNYG RSGEITKIRR KLTYQFSEAI

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against SPIC. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 248 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SPIC (ABIN2779513)

Zhu, Schweitzer, Romer, Sulentic, DeKoter: "Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling." dans: European journal of immunology, Vol. 38, Issue 9, pp. 2587-99, (2008) (PubMed).

Détails sur SPIC

Antigène: SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

Autre désignation: SPIC (SPIC Produits)

Synonymes: anticorps SPI-C, anticorps AU019198, anticorps C76795, anticorps Prf, anticorps Spi-C, anticorps zgc:101790, anticorps spi-c, anticorps spic, anticorps Spi-C transcription factor, anticorps transcription factor Spi-C-like, anticorps Spi-C transcription factor (Spi-1/PU.1 related), anticorps Spi-C transcription factor (Spi-1/PU.1 related) S homeolog, anticorps SPIC, anticorps LOC100349167, anticorps Spic, anticorps spic, anticorps spic.S

Sujet: SPIC controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. SPIC Regulates VCAM1 gene expression.
Alias Symbols: MGC40611, SPI-C
Protein Interaction Partner: APP,
Protein Size: 248

Poids moléculaire: 29 kDa

ID gène: 121599

NCBI Accession: NM_152323, NP_689536

UniProt: Q8N5J4