ETV5 anticorps (N-Term)

N° du produit ABIN2779534

Détail du produit anti-ETV5 anticorps

Antigène: ETV5 (Ets Variant 5 (ETV5))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ETV5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: AQVPDDEQFV PDFQSDNLVL HAPPPTKIKR ELHSPSSELS SCSHEQALGA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ETV5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ETV5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 510 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ETV5

Antigène: ETV5 (Ets Variant 5 (ETV5))

Autre désignation: ETV5 (ETV5 Produits)

Synonymes: anticorps ERM, anticorps etv5, anticorps fj87h10, anticorps id:ibd5133, anticorps wu:fj87h10, anticorps zgc:55647, anticorps 1110005E01Rik, anticorps 8430401F14Rik, anticorps ETS variant 5, anticorps ets variant 5, anticorps ets variant 5a, anticorps ETV5, anticorps Etv5, anticorps etv5a

Sujet: ETV5 Contains 1 ETS DNA-binding domain and belongs to the ETS family. The ETV5 gene expression is regulated by the conventional PKC (cPKC) pathway.ETV5 is subject to SUMO modification and this post-translational modification causes inhibition of transcription-enhancing activity Phosphorylated ETV5 and the actin cytoskeleton regulate CD44-mediated hyaluronan binding in myeloid cells. ERMs (ezrin/radixin/moesin) function as adaptor molecules in the interactions of adhesion receptors and intracellular tyrosine kinases. ETV5 can cooperate with c-Jun and has a role in progression of breast cancer
Alias Symbols: ERM
Protein Interaction Partner: RFWD2, HDAC11, DHRS7, SEZ6L2, SLC22A2, HOXD9, CYP3A5, CCR5, CISH, AMH, APP, BRCA1, ELAVL1, SUMO2, UBC, AR,
Protein Size: 510

Poids moléculaire: 58 kDa

ID gène: 2119

NCBI Accession: NM_004454, NP_004445

UniProt: P41161

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development