SNW1 anticorps (N-Term)

N° du produit ABIN2779548

Détail du produit anti-SNW1 anticorps

Antigène: SNW1 (SNW Domain Containing 1 (SNW1))

Épitope: N-Term

Reactivité: Humain, Souris, Chien, Boeuf (Vache), Cheval, Porc, Lapin, Rat, Cobaye, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNW1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: RQGQSKDKVI YSKYTDLVPK EVMNADDPDL QRPDEEAIKE ITEKTRVALE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%

Attributs du produit: This is a rabbit polyclonal antibody against SKIIP. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SKIIP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 536 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SNW1

Antigène: SNW1 (SNW Domain Containing 1 (SNW1))

Autre désignation: SKIIP (SNW1 Produits)

Synonymes: anticorps Gle1l1, anticorps Skiip, anticorps bx42, anticorps ncoa-62, anticorps prp45, anticorps prpf45, anticorps skiip, anticorps skip, anticorps Bx42, anticorps NCOA-62, anticorps PRPF45, anticorps Prp45, anticorps SKIIP, anticorps SKIP, anticorps 2310008B08Rik, anticorps AW048543, anticorps NCoA-62, anticorps SNW domain containing 1, anticorps nuclear protein SkiP, anticorps puff-specific protein Bx42, anticorps putative nuclear protein SkiP, anticorps GLE1 RNA export mediator homolog (yeast), pseudogene 1, anticorps SNW domain containing 1 S homeolog, anticorps snw1, anticorps PVX_002605, anticorps LOC5564605, anticorps Smp_105860, anticorps UREG_03916, anticorps Gle1-ps1, anticorps snw1.S, anticorps SNW1, anticorps Snw1

Sujet: SKIIP (Nuclear Protein SkiP, nuclear receptor coactivator NCoA-62, ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.
Alias Symbols: Bx42, SKIP, Prp45, SKIIP, PRPF45, NCOA-62
Protein Interaction Partner: TRAF1, GOLGA2, KRT40, LZTS2, RINT1, TEX11, CEP55, PPIL1, TFIP11, MTUS2, IKZF1, TP53, TUBGCP3, AURKB, UBC, SUZ12, RNF2, BMI1, HECW2, HDAC11, Dlg4, TTC14, ZNF830, SNIP1, CXorf56, XAB2, CTNNBL1, SART1, NHP2L1, MFAP1, EIF4A3, MAGOH, DHX15, DDX5, PABPC1, SKIV2
Protein Size: 536

Poids moléculaire: 61 kDa

ID gène: 22938

NCBI Accession: NM_012245, NP_036377

UniProt: Q13573

Pathways: Retinoic Acid Receptor Signaling Pathway