SCMH1 anticorps (Middle Region)
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- Antigène Voir toutes SCMH1 Anticorps
- SCMH1 (Sex Comb On Midleg Homolog 1 (SCMH1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cheval, Saccharomyces cerevisiae, Cobaye, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SCMH1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- KTAEPLKFPK KRGPKPGSKR KPRTLLNPPP ASPTTSTPEP DTSTVPQDAA
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 92%
- Attributs du produit
- This is a rabbit polyclonal antibody against SCMH1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human SCMH1
- Top Product
- Discover our top product SCMH1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 591 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- SCMH1 (Sex Comb On Midleg Homolog 1 (SCMH1))
- Autre désignation
- SCMH1 (SCMH1 Produits)
- Sujet
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SCMH1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Alias Symbols: Scml3
Protein Interaction Partner: UBQLN1, RNF2, MAGEA12, BMI1, UBQLN4, PHC3, CBX4, PCGF2, PHC2, PHC1, MAML3, LZTR1, PCBD1, EWSR1, TMEM11, SCMH1, MOB4, TOB1, POLR2M, LYPLA2, GMNN, HK1, Cbx2,
Protein Size: 591 - Poids moléculaire
- 65 kDa
- ID gène
- 22955
- NCBI Accession
- NM_012236, NP_036368
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