POU1F1 anticorps (Middle Region)
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- Antigène Voir toutes POU1F1 Anticorps
- POU1F1 (POU Class 1 Homeobox 1 (POU1F1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Chévre, Mouton, Cheval, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp POU1F1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- KRRTTISIAA KDALERHFGE QNKPSSQEIM RMAEELNLEK EVVRVWFCNR
- Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Sheep: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against POU1F1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human POU1F1
- Top Product
- Discover our top product POU1F1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 291 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- POU1F1 (POU Class 1 Homeobox 1 (POU1F1))
- Autre désignation
- POU1F1 (POU1F1 Produits)
- Synonymes
- anticorps CPHD1, anticorps GHF-1, anticorps PIT1, anticorps POU1F1a, anticorps Pit-1, anticorps Hmp1, anticorps Pit1, anticorps Pit1-rs1, anticorps dw, anticorps dwarf, anticorps GHF1, anticorps GHF1A, anticorps PIT1Z, anticorps PIT-1, anticorps Pit-1*, anticorps pit1, anticorps pit-1, anticorps POU class 1 homeobox 1, anticorps POU domain, class 1, transcription factor 1, anticorps POU1F1, anticorps Pou1f1, anticorps pou1f1
- Sujet
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PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP. This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: GHF-1, PIT1, Pit-1, Pit-1 beta, CPHD1, POU1F1a
Protein Interaction Partner: CEBPD, NCOR1, CREBBP, MED1, GATA2, NR1I3, NR1I2, PITX1, JUN, ETS1, NR3C1, VDR, PPARG, PPARA,
Protein Size: 291 - Poids moléculaire
- 33 kDa
- ID gène
- 5449
- NCBI Accession
- NM_000306, NP_000297
- UniProt
- P28069
- Pathways
- Regulation of Carbohydrate Metabolic Process
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