HNF1B anticorps (N-Term)
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- Antigène Voir toutes HNF1B Anticorps
- HNF1B (HNF1 Homeobox B (HNF1B))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Boeuf (Vache), Cheval, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HNF1B est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LETLPLSPGS GAEPDTKPVF HTLTNGHAKG RLSGDEGSED GDDYDTPPIL
- Specificité
- 100 % specific to all three isoforms of HNF1B (61, 58, 45kD).
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against HNF1B. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human HNF1B
- Top Product
- Discover our top product HNF1B Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 399 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- HNF1B (HNF1 Homeobox B (HNF1B))
- Autre désignation
- HNF1B (HNF1B Produits)
- Synonymes
- anticorps FJHN, anticorps HNF-1B, anticorps HNF1beta, anticorps HNF2, anticorps HPC11, anticorps LF-B3, anticorps LFB3, anticorps MODY5, anticorps TCF-2, anticorps TCF2, anticorps VHNF1, anticorps HNF-1b, anticorps HNF1B, anticorps AI385728, anticorps AI987804, anticorps HNF-1Beta, anticorps Hnf1beta, anticorps Tcf-2, anticorps Tcf2, anticorps vHNF1, anticorps vHNF-1, anticorps chunp6877, anticorps hnf1b, anticorps mst, anticorps tcf2, anticorps vhnf1, anticorps lfb3, anticorps hnf-1beta, anticorps hnf1-beta, anticorps hnf1beta, anticorps HNF1g, anticorps wu:fc23f06, anticorps HNF1 homeobox B, anticorps HNF1 homeobox Ba, anticorps HNF1 homeobox B S homeolog, anticorps HNF1 homeobox B L homeolog, anticorps HNF1 homeobox Bb, anticorps HNF1B, anticorps Hnf1b, anticorps hnf1ba, anticorps hnf1b.S, anticorps hnf1b.L, anticorps hnf1bb
- Sujet
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Hepatocyte Nuclear Factor 1-. (HNF-1., Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor ) is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1, depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5). A third human transcript variant is believed to exist based on such a variant in the rat: however, to date such an mRNA species has not been isolated.
Alias Symbols: FJHN, HNF1beta, HNF2, LFB3, MODY5, TCF2, VHNF1, HPC11, LF-B3
Protein Interaction Partner: HIST1H3A, PCBD1, CREBBP, HNF1A, ATF1, CREB1,
Protein Size: 399 - Poids moléculaire
- 45 kDa
- ID gène
- 6928
- NCBI Accession
- NM_006481, NP_006472
- UniProt
- P35680
- Pathways
- Hormone Transport, Stem Cell Maintenance, Tube Formation
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