TLE2 anticorps (N-Term)
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- Antigène Voir toutes TLE2 Anticorps
- TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TLE2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- VEEERPSGPG GGGKQRADEK EPSGPYESDE DKSDYNLVVD EDQPSEPPSP
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 85%, Pig: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against TLE2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human TLE2
- Top Product
- Discover our top product TLE2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 743 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))
- Autre désignation
- TLE2 (TLE2 Produits)
- Synonymes
- anticorps TLE2, anticorps ESG, anticorps ESG2, anticorps GRG2, anticorps Grg2, anticorps mKIAA4188, anticorps transducin like enhancer of split 2, anticorps transducin-like enhancer of split 2, anticorps TLE2, anticorps Tle2
- Sujet
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TLE2 belongs to the WD repeat Groucho/TLE family. It contains 6 WD repeats. TLE2 is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Alias Symbols: ESG, ESG2, FLJ41188, GRG2
Protein Interaction Partner: UBC, SUMO1, ORF50, LEF1, BARHL1, TLX3, VENTX, CUL4A, CUL4B, PAX9, MSX2, MSX1, FOXA3, EMX2, PRDM1, H3F3B, TLE1, UTY, HMGB1, RUNX1, TLE2, HES1,
Protein Size: 743 - Poids moléculaire
- 80 kDa
- ID gène
- 7089
- NCBI Accession
- NM_003260, NP_003251
- UniProt
- Q04725
- Pathways
- Signalisation WNT
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