TLE4 anticorps (N-Term)
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- Antigène Voir toutes TLE4 Anticorps
- TLE4 (Transducin-like Enhancer Protein 4 (TLE4))
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Épitope
- N-Term
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Reactivité
- Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TLE4 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- GAEKHRNSAD YSSESKKQKT EEKEIAARYD SDGEKSDDNL VVDVSNEDPS
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against TLE4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human TLE4
- Top Product
- Discover our top product TLE4 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 773 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TLE4 (Transducin-like Enhancer Protein 4 (TLE4))
- Autre désignation
- TLE4 (TLE4 Produits)
- Sujet
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TLE4 is the transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Alias Symbols: BCE-1, E(spI), ESG, ESG4, GRG4, BCE1
Protein Interaction Partner: SRPK2, POU2F2, UBC, LIG4, BRCA1, WDR77, PRMT5, PPM1B, CUX1, OTX1, OTX2, TLE4, PAX5, POU2F1, MSX1, HDAC1,
Protein Size: 773 - Poids moléculaire
- 84 kDa
- ID gène
- 7091
- NCBI Accession
- NM_007005, NP_008936
- UniProt
- Q04727
- Pathways
- Signalisation WNT
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