SIRT4 anticorps (Middle Region)

N° du produit ABIN2779654

Détail du produit anti-SIRT4 anticorps

Antigène: SIRT4 (Sirtuin 4 (SIRT4))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cheval, Lapin, Mouton, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: QVPTCVQCGG HLKPDVVFFG DTVNPDKVDF VHKRVKEADS LLVVGSSLQV

Homologie: Cow: 93%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 93%, Rat: 93%, Sheep: 92%

Attributs du produit: This is a rabbit polyclonal antibody against SIRT4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SIRT4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 314 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SIRT4

Antigène: SIRT4 (Sirtuin 4 (SIRT4))

Autre désignation: SIRT4 (SIRT4 Produits)

Synonymes: anticorps SIRT4, anticorps im:7139453, anticorps SIR2L4, anticorps 4930596O17Rik, anticorps sirtuin 4, anticorps SIRT4, anticorps sirt4, anticorps Sirt4

Sujet: SIRT4 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT4 is included in class IV of the sirtuin family.This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
Alias Symbols: MGC130046, MGC130047, MGC57437, SIR2L4, sirtuin 4
Protein Interaction Partner: SKP2, Glud1, UBC, SIRT3, IDE, SLC25A6, SLC25A5,
Protein Size: 314

Poids moléculaire: 35 kDa

ID gène: 23409

NCBI Accession: NM_012240, NP_036372

UniProt: Q9Y6E7

Pathways: Negative Regulation of Hormone Secretion