POLR2B anticorps (N-Term)
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- Antigène Voir toutes POLR2B Anticorps
- POLR2B (Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp POLR2B est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- TYSAPLYVDI TKTVIKEGEE QLQTQHQKTF IGKIPIMLRS TYCLLNGLTD
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against POLR2B. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human POLR2B
- Top Product
- Discover our top product POLR2B Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1174 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- POLR2B (Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B))
- Autre désignation
- POLR2B (POLR2B Produits)
- Synonymes
- anticorps Pol2rb, anticorps Rpb140, anticorps Rpb2, anticorps POL2RB, anticorps RPB2, anticorps hRPB140, anticorps hsRPB2, anticorps RNA polymerase II subunit B, anticorps polymerase (RNA) II (DNA directed) polypeptide B, 140kDa, anticorps DNA-directed RNA polymerase II subunit RPB2, anticorps polymerase (RNA) II (DNA directed) polypeptide B, anticorps polymerase (RNA) II (DNA directed) polypeptide B, 140kDa L homeolog, anticorps POLR2B, anticorps polr2b, anticorps LOC100640211, anticorps Polr2b, anticorps polr2b.L, anticorps rpb-2
- Sujet
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POLR2B is the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA.
Alias Symbols: RPB2, POL2RB, hsRPB2, hRPB140
Protein Interaction Partner: ESR1, UBC, TCEB3, SRC, PSMB9, SUMO2, XRN2, WWOX, SUZ12, RNF2, NEDD4, ITCH, RABEP2, HECW2, FBXO6, CDK20, HDAC11, ILK, POLR2C, MED19, MED26, RECQL5, VCP, BARD1, MDC1, POLR3F, TUBB4B, TUBA4A, POLR2I, POLR2E, POLR2D, POLR2A, DCTN1, ATP6V1B2, MEN1, CDK7, CCNH,
Protein Size: 1174 - Poids moléculaire
- 134 kDa
- ID gène
- 5431
- NCBI Accession
- NM_000938, NP_000929
- UniProt
- P30876
- Pathways
- Regulatory RNA Pathways, Réparation de l'ADN
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