KAT2B anticorps (N-Term)
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- Antigène Voir toutes KAT2B Anticorps
- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KAT2B est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LFKLLRKSIL QRGKPVVEGS LEKKPPFEKP SIEQGVNNFV QYKFSHLPAK
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 90%
- Attributs du produit
- This is a rabbit polyclonal antibody against PCAF. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCAF
- Top Product
- Discover our top product KAT2B Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 832 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
- Autre désignation
- PCAF (KAT2B Produits)
- Synonymes
- anticorps PCAF, anticorps pcaf, anticorps si:ch211-1j13.2, anticorps zgc:161980, anticorps gb:dq017634, anticorps im:7156024, anticorps CAF, anticorps P, anticorps P/CAF, anticorps A930006P13Rik, anticorps AI461839, anticorps AW536563, anticorps Pcaf, anticorps p/CAF, anticorps lysine acetyltransferase 2B, anticorps K(lysine) acetyltransferase 2B, anticorps K(lysine) acetyltransferase 2A, anticorps KAT2B, anticorps kat2b, anticorps kat2a, anticorps Kat2b
- Sujet
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CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. PCAF associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
Alias Symbols: P, CAF, PCAF, P/CAF
Protein Interaction Partner: MDM2, HNRNPD, ACLY, KLF2, E2F1, VHL, IRF1, TAL1, TAF12, TAF10, TAF9, TADA2A, RB1, HIST1H1B, TAF5L, TAF6L, TADA3, SUPT3H, TWIST1, PDK1, AKT1, UBC, SIAH2, UBE2D3, UBE2D1, TP73, TP53, SRC, PGR, YEATS2, MBIP, WDR5, PTEN, DR1, HIF1A, HIST2H3C, CHEK2, HIST1H4A,
Protein Size: 832 - Poids moléculaire
- 93 kDa
- ID gène
- 8850
- NCBI Accession
- NM_003884, NP_003875
- UniProt
- Q92831
- Pathways
- Signalisation p53, Regulation of Carbohydrate Metabolic Process
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