SUV39H1 anticorps (N-Term)

N° du produit ABIN2779665

Détail du produit anti-SUV39H1 anticorps

Antigène: SUV39H1 (Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUV39H1 est non-conjugé

Application: Western Blotting (WB)

Séquence: RHLDPSLANY LVQKAKQRRA LRRWEQELNA KRSHLGRITV ENEVDLDGPP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SUV39H1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SUV39H1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 412 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SUV39H1

Antigène: SUV39H1 (Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))

Autre désignation: SUV39H1 (SUV39H1 Produits)

Synonymes: anticorps H3-K9-HMTase 1, anticorps KMT1A, anticorps MG44, anticorps SUV39H, anticorps AI852103, anticorps AL022883, anticorps DXHXS7466e, anticorps mIS6, anticorps RGD1565028, anticorps kmt1a, anticorps suv39h, anticorps fe02c04, anticorps suv39h1, anticorps wu:fe02c04, anticorps zgc:101027, anticorps fe47h06, anticorps wu:fb18a10, anticorps wu:fe47h06, anticorps zgc:136593, anticorps suppressor of variegation 3-9 homolog 1, anticorps suppressor of variegation 3-9 homolog 1 (Drosophila), anticorps suppressor of variegation 3-9 homolog 1 L homeolog, anticorps suppressor of variegation 3-9 homolog 1a, anticorps suppressor of variegation 3-9 homolog 1b, anticorps SUV39H1, anticorps Suv39h1, anticorps suv39h1.L, anticorps suv39h1a, anticorps suv39h1b

Sujet: SUV39H1, a human homolog of the Drosophila position effect variegation modifier Su(var)3-9 and of the S. pombe silencing factor clr4, encodes a heterochromatic protein that transiently accumulates at centromeric positions during mitosis. This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: KMT1A, MG44, SUV39H
Protein Interaction Partner: LZTS2, CEP70, HOOK2, CBX5, KRTAP10-7, HIST2H3A, CDCA4, KLHDC4, GTPBP2, ZNF581, ZCCHC17, CRBN, ING4, DCAF8, KLF15, KLHL20, PHF19, IL16, IGFBP4, ID2, ID1, HOXC4, HOXA1, FYN, FUS, EZH2, CLK3, ATP6V1B1, ATF3, GTF2H2C_2, H3F3C, LHX8, STX19, C17orf82, ZNF829, C
Protein Size: 412

Poids moléculaire: 48 kDa

ID gène: 6839

NCBI Accession: NM_003173, NP_003164

UniProt: O43463