Src anticorps (N-Term)
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- Antigène Voir toutes Src Anticorps
- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Src est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MGSNKSKPKD ASQRRRSLEP AENVHGAGGG AFPASQTPSK PASADGHRGP
- Homologie
- Cow: 85%, Dog: 92%, Guinea Pig: 92%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against SRC. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human SRC
- Top Product
- Discover our top product Src Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 536 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
- Autre désignation
- SRC (Src Produits)
- Synonymes
- anticorps AW259666, anticorps pp60c-src, anticorps C-src1, anticorps CG7524, anticorps D-Src64B, anticorps D-src, anticorps DSRC64, anticorps DSrc, anticorps DSrc64, anticorps DSrc64B, anticorps Dm SRC1, anticorps DmHD-358, anticorps Dmel\CG7524, anticorps Dsrc, anticorps Dsrc64, anticorps Dsrc64B, anticorps HD-358, anticorps MRE5, anticorps SRC 64B, anticorps Src, anticorps Src1, anticorps Src64, anticorps c-src, anticorps dSrc, anticorps dsrc, anticorps src, anticorps src1, anticorps src64, anticorps src64B, anticorps src64b, anticorps ASV, anticorps SRC1, anticorps c-SRC, anticorps p60-Src, anticorps c-Src, anticorps PP60C-SCR, anticorps SDR, anticorps SRC proto-oncogene, non-receptor tyrosine kinase, anticorps uncharacterized LOC5574802, anticorps proto-oncogene tyrosine-protein kinase src, anticorps Rous sarcoma oncogene, anticorps Src oncogene at 64B, anticorps SRC, anticorps LOC5574802, anticorps CpipJ_CPIJ010659, anticorps Src, anticorps Src64B
- Classe de substances
- Viral Protein
- Sujet
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This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC protein is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: ASV, SRC1, c-SRC, p60-Src
Protein Interaction Partner: PSMB9, POLR2L, POLR2K, POLR2J, POLR2I, POLR2H, POLR2G, POLR2F, POLR2E, POLR2D, POLR2C, POLR2B, POLR2A, NEDD4, MAPT, ESR1, CA3, ARRB2, UBC, SRC, SPRR2A, IKBKG, CBLC, ZNF658B, TLR4, RGS16, PTGER4, EGFR, ARRB1, TNFRSF1A, KHDRBS1, SYK, CD44, ENO1, ANXA7, PIK3
Protein Size: 536 - Poids moléculaire
- 60 kDa
- ID gène
- 6714
- NCBI Accession
- NM_198291, NP_938033
- UniProt
- P12931
- Pathways
- Signalistation JAK/STAT, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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