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FOXP1 anticorps (N-Term)

FOXP1 Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Cobaye WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2779725
  • Antigène Voir toutes FOXP1 Anticorps
    FOXP1 (Forkhead Box P1 (FOXP1))
    Épitope
    • 16
    • 14
    • 13
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 76
    • 49
    • 25
    • 18
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Cobaye
    Hôte
    • 81
    • 13
    • 1
    Lapin
    Clonalité
    • 71
    • 23
    • 1
    Polyclonal
    Conjugué
    • 44
    • 8
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FOXP1 est non-conjugé
    Application
    • 48
    • 39
    • 33
    • 31
    • 12
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    MIPTELQQLW KEVTSAHTAE ETTGNNHSSL DLTTTCVSSS APSKTSLI
    Homologie
    Cow: 92%, Dog: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against FOXP1. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human FOXP1
    Top Product
    Discover our top product FOXP1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 677 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tang, Becanovic, Desplats, Spencer, Hill, Connolly, Masliah, Leavitt, Thomas: "Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease." dans: Human molecular genetics, Vol. 21, Issue 14, pp. 3097-111, (2012) (PubMed).

    Konstantoulas, Parmar, Li: "FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3." dans: Journal of neurochemistry, Vol. 113, Issue 4, pp. 836-47, (2010) (PubMed).

    Jepsen, Gleiberman, Shi, Simon, Rosenfeld: "Cooperative regulation in development by SMRT and FOXP1." dans: Genes & development, Vol. 22, Issue 6, pp. 740-5, (2008) (PubMed).

  • Antigène
    FOXP1 (Forkhead Box P1 (FOXP1))
    Autre désignation
    FOXP1 (FOXP1 Produits)
    Synonymes
    anticorps 12CC4, anticorps QRF1, anticorps hFKH1B, anticorps 3110052D19Rik, anticorps 4932443N09Rik, anticorps AI461938, anticorps AW494214, anticorps foxp1, anticorps im:7139058, anticorps wu:fc83a06, anticorps FOXP1, anticorps MGC145686, anticorps 12cc4, anticorps fkh1b, anticorps hspc215, anticorps qrf1, anticorps xlfoxp1, anticorps im:7146611, anticorps wu:fb97f01, anticorps zgc:154010, anticorps forkhead box P1, anticorps forkhead box P1b, anticorps forkhead box P1 S homeolog, anticorps forkhead box P1a, anticorps FOXP1, anticorps Foxp1, anticorps foxp1b, anticorps foxp1, anticorps foxp1.S, anticorps foxp1a
    Sujet
    FOXP1 belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s).
    Alias Symbols: QRF1, 12CC4, hFKH1B, HSPC215
    Protein Interaction Partner: SUMO2, MYC, IL3RA, ELAVL1, NCOR2, GATAD2B, MTA1, FOXP1, FOXP4, FOXP2, CTBP1,
    Protein Size: 677
    Poids moléculaire
    75 kDa
    ID gène
    27086
    NCBI Accession
    NM_032682, NP_116071
    UniProt
    Q9H334
    Pathways
    Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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