CIITA anticorps (C-Term)
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- Antigène Voir toutes CIITA Anticorps
- CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CIITA est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MALWESLQQQ GEAQLLQAAE EKFTIEPFKA KSPKDVEDLD RLVQTQRLRN
- Homologie
- Dog: 100%, Human: 79%, Mouse: 100%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against C2TA. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of mouse C2TA
- Top Product
- Discover our top product CIITA Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1078 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))
- Autre désignation
- C2TA (CIITA Produits)
- Synonymes
- anticorps CIITA, anticorps C2ta, anticorps EG669998, anticorps Gm9475, anticorps C2TA, anticorps CIITAIV, anticorps MHC2TA, anticorps NLRA, anticorps Mhc2ta, anticorps class II, major histocompatibility complex, transactivator, anticorps class II major histocompatibility complex transactivator, anticorps MHC class II transactivator, anticorps class II transactivator, anticorps CIITA, anticorps LOC710761, anticorps ciita, anticorps LOC100443575, anticorps Ciita, anticorps LOC100736732
- Sujet
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C2ta is essential for transcriptional activity of the HLA class II promoter, activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. C2ta may act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter
Alias Symbols: C2ta, Gm9475, EG669998
Protein Interaction Partner: Rfxank, Ssbp4, Ssbp3, Gmeb1, Cited4, Tcf3, Nfe2, Hoxa2, Ewsr1,
Protein Size: 1078 - Poids moléculaire
- 119 kDa
- ID gène
- 12265
- NCBI Accession
- NM_007575, NP_031601
- UniProt
- Q3U2P0
- Pathways
- Cancer Immune Checkpoints
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