FOXA3 anticorps (C-Term)

N° du produit ABIN2779850

Détail du produit anti-FOXA3 anticorps

Antigène: FOXA3 (Forkhead Box A3 (FOXA3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXA3 est non-conjugé

Application: Western Blotting (WB)

Séquence: YNFNHPFSIN NLMSEQTSTP SKLDVGFGGY GAESGEPGVY YQSLYSRSLL

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 86%, Mouse: 100%, Pig: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Foxa3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the c terminal region of mouse Foxa3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 353 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FOXA3

Antigène: FOXA3 (Forkhead Box A3 (FOXA3))

Autre désignation: Foxa3 (FOXA3 Produits)

Synonymes: anticorps FOXA3, anticorps Zffkh1, anticorps fa11c04, anticorps fkd2, anticorps forkhead-2, anticorps wu:fa11c04, anticorps wu:fc37a08, anticorps zf-FKH1, anticorps FKHH3, anticorps HNF3G, anticorps TCF3G, anticorps HNF3-G, anticorps Hnf-3g, anticorps Hnf3g, anticorps Tcf-3g, anticorps Tcf3g, anticorps forkhead box A3, anticorps FOXA3, anticorps foxa3, anticorps Foxa3

Sujet: Foxa3 is a transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Foxa3 is originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Foxa3 interacts with the cis-acting regulatory regions of these genes.Foxa3 is involved in glucose homeostasis, activates GLUT2 transcription and regulation of neuronal-specific transcription. Foxa3 is also involved in regulation of spermatogenesis, required for the maintenance of the testicular germ cell population and male fertility.
Alias Symbols: Hnf-3g, Hnf3g, Tcf-3g, Tcf3g
Protein Size: 353

Poids moléculaire: 37 kDa

ID gène: 15377

NCBI Accession: NM_008260, NP_032286

UniProt: P35584

Pathways: Carbohydrate Homeostasis