Mesp2 anticorps (C-Term)

N° du produit ABIN2779870

Détail du produit anti-Mesp2 anticorps

Antigène: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Épitope: C-Term

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mesp2 est non-conjugé

Application: Western Blotting (WB)

Séquence: SCQRLQPQPQ PQPQWGCWGH DAEVLSTSED QGSSPALQLP VASPTPSSGL

Homologie: Mouse: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MESP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of mouse MESP2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 370 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Mesp2 (ABIN2779870)

Leschik, Stefanovic, Brinon, Pucéat: "Cardiac commitment of primate embryonic stem cells." dans: Nature protocols, Vol. 3, Issue 9, pp. 1381-7, (2008) (PubMed).

Détails sur Mesp2

Antigène: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Autre désignation: MESP2 (Mesp2 Produits)

Synonymes: anticorps bHLHc6, anticorps SCDO2, anticorps mesoderm posterior 2, anticorps mesoderm posterior bHLH transcription factor 2, anticorps Mesp2, anticorps MESP2

Sujet: Somite boundaries formed during embryogenesis, at the interface between Notch1-activated and -repressed domains. Genetic and biochemical studies indicate that this interface is generated by suppression of Notch activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe gene (Lfng). It is proposed that the oscillation of Notch activity is arrested and translated in the wavefront by Mesp2.
Alias Symbols: bHLHc6
Protein Interaction Partner: Lfng,
Protein Size: 370

Poids moléculaire: 41 kDa

ID gène: 17293

NCBI Accession: NM_008589, NP_032615

UniProt: O08574