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MCAF1 anticorps (Middle Region)

ATF7IP Reactivité: Porc, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2780013
  • Antigène Voir toutes MCAF1 (ATF7IP) Anticorps
    MCAF1 (ATF7IP) (Activating Transcription Factor 7 Interacting Protein (ATF7IP))
    Épitope
    • 3
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    Porc, Souris, Rat
    Hôte
    • 6
    • 2
    Lapin
    Clonalité
    • 6
    • 2
    Polyclonal
    Conjugué
    • 8
    Cet anticorp MCAF1 est non-conjugé
    Application
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MSTPEGEKSE KDGKAEEEER VPAEEQPPVR NEFSRRKRSK SEDMDSVESK
    Homologie
    Mouse: 100%, Pig: 92%, Rat: 85%
    Attributs du produit
    This is a rabbit polyclonal antibody against Atf7ip. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of Mouse Atf7ip
    Top Product
    Discover our top product ATF7IP Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1306 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    MCAF1 (ATF7IP) (Activating Transcription Factor 7 Interacting Protein (ATF7IP))
    Autre désignation
    Atf7ip (ATF7IP Produits)
    Synonymes
    anticorps ATF7IP, anticorps AM, anticorps MCAF, anticorps MCAF1, anticorps p621, anticorps 2610204M12Rik, anticorps Mcaf1, anticorps fa12g02, anticorps wu:fa12g02, anticorps zgc:152981, anticorps activating transcription factor 7 interacting protein, anticorps Atf7ip, anticorps ATF7IP, anticorps atf7ip
    Sujet
    Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Atf7ip can both act as an activator or a repressor depending on the context. It mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Atf7ip is required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3). Atf7ip may have ATPase activity.
    Alias Symbols: 2610204M12Rik, AM, Mcaf1
    Protein Interaction Partner: Atf7, Gtf2f1, Gtf2e2, Aagab, Ccnh, Gtf2h1, Ercc3, Cdk7, C1qbp, POLR2H, POLR2G, POLR2D, POLR2C,
    Protein Size: 1306
    Poids moléculaire
    138 kDa
    ID gène
    54343
    NCBI Accession
    NM_019426, NP_062299
    UniProt
    Q7TT18
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