MAFA anticorps (C-Term)
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- Antigène Voir toutes MAFA Anticorps
- MAFA (Transcription Factor MafA (MAFA))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MAFA est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- KLEVGRLAKE RDLYKEKYEK LAGRGGPGGA GGAGFPREPS PAQAGPGAAK
- Homologie
- Human: 86%, Mouse: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against Mafa. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product MAFA Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 359 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- MAFA (Transcription Factor MafA (MAFA))
- Autre désignation
- Mafa (MAFA Produits)
- Synonymes
- anticorps RIPE3b1, anticorps hMafA, anticorps RGD1562627, anticorps 2F1-Ag, anticorps MAFA, anticorps MAFA-L, anticorps SMaf1, anticorps mafl, anticorps L-MAF, anticorps MAFL, anticorps Maf, anticorps v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian), anticorps MAF bZIP transcription factor A, anticorps killer cell lectin-like receptor subfamily G, member 1, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa, anticorps monocyte to macrophage differentiation-associated, anticorps Mafa, anticorps MAFA, anticorps Klrg1, anticorps mafa, anticorps mafaa, anticorps Mmd
- Sujet
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Mafa acts as a transcriptional factor. Mafa specifically binds the insulin enhancer element RIPE3b. Mafa cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Mafa regulates the insulin gene transcription. Mafa is involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Alias Symbols: RIPE3b1
Protein Interaction Partner: Psme3,
Protein Size: 359 - Poids moléculaire
- 37 kDa
- ID gène
- 378435
- NCBI Accession
- NM_194350, NP_919331
- UniProt
- Q8CF90
- Pathways
- Hormone Transport
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