ZNF265 anticorps (N-Term)

N° du produit ABIN2780239

Détail du produit anti-ZNF265 anticorps

Antigène: ZNF265 (Zranb2) (Zinc Finger Protein 265 (Zranb2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF265 est non-conjugé

Application: Western Blotting (WB)

Séquence: RCGREKTTEA KMMKAGGTEI GKTLAEKSRG LFSANDWQCK TCSNVNWARR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ZNF265. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF265

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 330 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ZNF265 (ABIN2780239)

Wang, Du, Li, Zhang: "Identification of the Zinc Finger Protein ZRANB2 as a Novel Maternal Lipopolysaccharide-binding Protein That Protects Embryos of Zebrafish against Gram-negative Bacterial Infections." dans: The Journal of biological chemistry, Vol. 291, Issue 8, pp. 4019-34, (2016) (PubMed).

Détails sur ZNF265

Antigène: ZNF265 (Zranb2) (Zinc Finger Protein 265 (Zranb2))

Autre désignation: ZNF265 (Zranb2 Produits)

Synonymes: anticorps ZNF265, anticorps ZRANB2, anticorps c4sr, anticorps zis, anticorps zis1, anticorps zis2, anticorps znf265, anticorps zranb2, anticorps ZIS, anticorps ZIS1, anticorps ZIS2, anticorps AI227013, anticorps Zfp265, anticorps Zis, anticorps Znf265, anticorps zinc finger RANBP2-type containing 2, anticorps zinc finger RANBP2-type containing 2 L homeolog, anticorps zinc finger, RAN-binding domain containing 2, anticorps ZRANB2, anticorps zranb2.L, anticorps Zranb2

Sujet: ZNF265 is a protein that has been shown to bind to the spliceosomal components U1-70K and U2AF35 and to direct alternative splicing. Analysis of the structure reveals substantial similarity to known RNA-binding motifs in terms of the distribution of key surface residues responsible for making RNA contacts, despite a complete lack of structural homology. An RNA gel shift assay was used to demonstrate that a single crossed finger domain from ZNF265 is capable of binding to an RNA message. Taken together, these results define a new RNA-binding motif and should provide insight into the functions of the >100 uncharacterized proteins in the sequence data bases that contain this domain.
Alias Symbols: ZIS, ZIS1, ZIS2, ZNF265
Protein Interaction Partner: UBC, C18orf25, TBC1D17, CORO1B, PARVA, SWAP70, OSBP, CDK1, FBXL7, SRPK2, SRPK1, CSNK2A1, KIF20A, SMURF1, UBE2B, UBA52, TYMS, TTC1, SULT1A1, SRSF7, PSMA1, PCMT1, UCHL3, UBE2V2, TTC9C, SRXN1, UNK, UBL7, ZNF644, UBQLN1, UBQLN2, UBXN7, TTLL12, UBE2C, AHCYL1,
Protein Size: 330

Poids moléculaire: 37 kDa

ID gène: 9406

NCBI Accession: NM_203350, NP_976225

UniProt: Q5VV34