SOX9 anticorps (C-Term)

N° du produit ABIN2780338

Détail du produit anti-SOX9 anticorps

Antigène: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Lapin, Chien, Porc, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOX9 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Séquence: AGQGTGLYST FTYMNPAQRP MYTPIADTSG VPSIPQTHSP QHWEQPVYTQ

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SOX9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human SOX9

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 509 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SOX9 (ABIN2780338)

Lau, Lee, Chang: "Conserved sex-specific timing of meiotic initiation during sex differentiation in the protandrous black porgy Acanthopagrus schlegelii." dans: Biology of reproduction, Vol. 88, Issue 6, pp. 150, (2013) (PubMed).

Détails sur SOX9

Antigène: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Autre désignation: SOX9 (SOX9 Produits)

Synonymes: anticorps CMD1, anticorps CMPD1, anticorps SRA1, anticorps LOC100227849, anticorps 2010306G03Rik, anticorps AV220920, anticorps mKIAA4243, anticorps SOX-9, anticorps cmd1, anticorps cmpd1, anticorps sox-9, anticorps sox9, anticorps sox9-a, anticorps sox9-b, anticorps sox9b, anticorps sra1, anticorps SRY-box 9, anticorps transcription factor SOX-9, anticorps SRY (sex determining region Y)-box 9, anticorps SRY box 9, anticorps SRY-box 9 L homeolog, anticorps SOX9, anticorps LOC100227849, anticorps Sox9, anticorps sox9.L

Sujet: SOX9 recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMD1, CMPD1, SRA1
Protein Interaction Partner: ZBTB7A, SCX, HERC1, UBC, SOX9, ATP6V1H, ctnnb1-a, RUNX2, SMAD3, SMAD2, EP300, CREB3L4, SPEN, KPNB1, TRAF2, CREBBP, MED12, NR5A1, MAF, HSPA1A, CREB1,
Protein Size: 509

Poids moléculaire: 56 kDa

ID gène: 6662

NCBI Accession: NM_000346, NP_000337

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development