Elf4 anticorps (N-Term)

N° du produit ABIN2780359

Détail du produit anti-Elf4 anticorps

Antigène: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Elf4 est non-conjugé

Application: Western Blotting (WB)

Séquence: MAITLQPSDL IFEFASNGMD DDIHQLEDPS VFPAVIVEQV PYPDLLHLYS

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ELF4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ELF4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 663 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Elf4

Antigène: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Autre désignation: ELF4 (Elf4 Produits)

Synonymes: anticorps ELF4, anticorps RGD1560743, anticorps ELFR, anticorps MEF, anticorps AV314029, anticorps BC042423, anticorps ENSMUSG00000053512, anticorps Gm9907, anticorps Mef, anticorps E74 like ETS transcription factor 4, anticorps E74-like factor 4 (ets domain transcription factor), anticorps ELF4, anticorps Elf4

Sujet: ELF4 contains 1 ETS DNA-binding domain and belongs to the ETS family. It is transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. It transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. It acts synergistically with RUNX1 to transactivate the IL3 promoter and also transactivates the PRF1 promoter in natural killer (NK) cells. ELF4 plays a role in the development and function of NK and NK T-cells and in innate immunity.
Alias Symbols: MEF, ELFR
Protein Interaction Partner: NPM1, SET, CASP4, UBC, PML, SKP2, KDM5B, FBXO4, FBXO7, UBB, RUNX1,
Protein Size: 663

Poids moléculaire: 71 kDa

ID gène: 2000

NCBI Accession: NM_001421, NP_001412

UniProt: Q99607

Pathways: Positive Regulation of Endopeptidase Activity