FOXO3 anticorps (N-Term)
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- Antigène Voir toutes FOXO3 Anticorps
- FOXO3 (Forkhead Box O3 (FOXO3))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Mouton, Lapin, Cobaye, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FOXO3 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MAEAPASPAP LSPLEVELDP EFEPQSRPRS CTWPLQRPEL QASPAKPSGE
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 75%
- Attributs du produit
- This is a rabbit polyclonal antibody against FOXO3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human FOXO3
- Top Product
- Discover our top product FOXO3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 673 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- FOXO3 (Forkhead Box O3 (FOXO3))
- Autre désignation
- FOXO3 (FOXO3 Produits)
- Sujet
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FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia.This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
Alias Symbols: AF6q21, DKFZp781A0677, FKHRL1, FKHRL1P2, FOXO2, FOXO3A, MGC12739, MGC31925
Protein Interaction Partner: SMAD3, YWHAB, ERBB2IP, SIRT1, YWHAE, CDK6, AKT1, IKBKB, CHUK, CDT1, UBC, SKP2, MAPK1, PCNA, MDM2, BTRC, CREBBP, ELAVL1, SMAD4, MAPK6, NR1H3, NR1H2, NLK, VDR, SMAD1, EP300, STK4, FANCD2, RAD17, MYC, H2AFX, BRCA1, ATM, SIRT3, ATG101, YWHAH, PGK1, GBAS, FKBP
Protein Size: 673 - Poids moléculaire
- 71 kDa
- ID gène
- 2309
- NCBI Accession
- NM_001455, NP_001446
- UniProt
- O43524
- Pathways
- Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
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