TADA2L anticorps (Middle Region)

N° du produit ABIN2780370

Détail du produit anti-TADA2L anticorps

Antigène: TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TADA2L est non-conjugé

Application: Western Blotting (WB)

Séquence: LEYKSALLNE CNKQGGLRLA QARALIKIDV NKTRKIYDFL IREGYITKG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against TADA2L. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TADA2L

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 443 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TADA2L (ABIN2780370)

Thompson, Yang, Power, Hufschmid, Beveridge, Reid, Ng, Armson, Ryan: "Identification of zoonotic Giardia genotypes in marsupials in Australia." dans: Experimental parasitology, Vol. 120, Issue 1, pp. 88-93, (2008) (PubMed).

Détails sur TADA2L

Antigène: TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

Autre désignation: TADA2L (TADA2A Produits)

Synonymes: anticorps MGC81519, anticorps TADA2A, anticorps TADA2L, anticorps ADA2, anticorps ADA2A, anticorps hADA2, anticorps AV319371, anticorps D030022J10Rik, anticorps Tada2l, anticorps tada2l, anticorps zgc:154057, anticorps transcriptional adaptor 2A L homeolog, anticorps transcriptional adaptor 2A, anticorps tada2a.L, anticorps TADA2A, anticorps Tada2a, anticorps tada2a

Sujet: Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. TADA2L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Two transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: ADA2, FLJ12705, KL04P, hADA2, ADA2A, TADA2L
Protein Interaction Partner: MFAP1, MAGOH, KPNA2, FBF1, PRPF31, PPP1R16B, ZFYVE26, SF3A3, FARS2, MTX2, EIF4E2, FAM127C, KLHL38, TTC9C, ZNF564, TEKT4, LOC149950, KLC4, TTC23, GPSM3, CDCA7L, C1orf109, CCHCR1, PRKAB2, ARNT2, USP22, TADA3, HNF4A, LYN, HSP90AA1, KAT2B, MCPH1, PAXIP1, SUPT
Protein Size: 443

Poids moléculaire: 51 kDa

ID gène: 6871

NCBI Accession: NM_001488, NP_001479

UniProt: O75478

Pathways: Chromatin Binding