IGHMBP2 anticorps (N-Term)

N° du produit ABIN2780407

Détail du produit anti-IGHMBP2 anticorps

Antigène: IGHMBP2 (Immunoglobulin mu Binding Protein 2 (IGHMBP2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGHMBP2 est non-conjugé

Application: Western Blotting (WB)

Séquence: QLLELERDAE VEERRSWQEH SSLRELQSRG VCLLKLQVSS QRTGLYGQRL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Ighmbp2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 993 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-IGHMBP2 (ABIN2780407)

Shababi, Feng, Villalon, Sibigtroth, Osman, Miller, Williams-Simon, Lombardi, Sass, Atkinson, Garcia, Ko, Lorson: "Rescue of a Mouse Model of Spinal Muscular Atrophy With Respiratory Distress Type 1 by AAV9-IGHMBP2 Is Dose Dependent." dans: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 24, Issue 5, pp. 855-66, (2016) (PubMed).

Détails sur IGHMBP2

Antigène: IGHMBP2 (Immunoglobulin mu Binding Protein 2 (IGHMBP2))

Autre désignation: Ighmbp2 (IGHMBP2 Produits)

Synonymes: anticorps NV12364, anticorps CATF1, anticorps HCSA, anticorps HMN6, anticorps SMARD1, anticorps SMUBP2, anticorps ZFAND7, anticorps AEP, anticorps Catf1, anticorps RIPE3b1, anticorps Smbp-2, anticorps Smbp2, anticorps Smubp2, anticorps nmd, anticorps sma, anticorps RIP-1, anticorps RIP1, anticorps immunoglobulin mu binding protein 2, anticorps IGHMBP2, anticorps Ighmbp2, anticorps ighmbp2

Sujet: Ighmbp2 is a 5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Ighmbp2 acts as a transcription regulator. Ighmbp2 is required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Ighmbp2 exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Ighmbp2 binds to the insulin II gene RIPE3B enhancer region. Ighmbp2 may be involved in translation.Ighmbp2 is a DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region.Ighmbp2 preferentially binds to the 5'-GGGCT-3' motif. Ighmbp2 interacts with tRNA-Tyr.
Alias Symbols: AEP, Catf1, RIPE3b1, Smbp-2, Smbp2, Smubp2, nmd, sma
Protein Interaction Partner: Gtf3c1, Hnrnph1, Ruvbl1, Abt1, Zbtb14, Tyr, Ighmbp2, Ruvbl2, Hspa1b, Slit3, Robo1,
Protein Size: 993

Poids moléculaire: 109 kDa

ID gène: 20589

NCBI Accession: NM_009212, NP_033238

UniProt: P40694