RFX1 anticorps (Middle Region)
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- Antigène Voir toutes RFX1 Anticorps
- RFX1 (Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Saccharomyces cerevisiae
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RFX1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- EDTDLSRLYT ATSLMQIDDN VMRKFHGYNS LKEYYEEESC MRYLHRIYVP
- Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 90%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against RFX1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human RFX1
- Top Product
- Discover our top product RFX1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 979 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- RFX1 (Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))
- Autre désignation
- RFX1 (RFX1 Produits)
- Synonymes
- anticorps EFC, anticorps RFX, anticorps AI047719, anticorps AI385641, anticorps zgc:162914, anticorps regulatory factor X1, anticorps regulatory factor X, 1 (influences HLA class II expression), anticorps regulatory factor X, 1a (influences HLA class II expression), anticorps RFX1, anticorps Rfx1, anticorps rfx1a
- Sujet
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RFX1 is a member of the regulatory factor X protein family, which are transcription factors that contain a highly-conserved winged helix DNA binding domain. RFX1 is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes. This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EF-C, EFC, RFX
Protein Interaction Partner: SOX2, SMAD9, SMAD4, SMAD1, NOTCH1, Cebpb, NCOA3, HDAC1, NFIC, NFIB, TADA3, RFX3, MAGED1, ABL1, NFIX, HMGB1, HIVEP2, RFX2, ADD1,
Protein Size: 979 - Poids moléculaire
- 105 kDa
- ID gène
- 5989
- NCBI Accession
- NM_002918, NP_002909
- UniProt
- P22670
- Pathways
- Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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