TEF anticorps (N-Term)

N° du produit ABIN2780494

Détail du produit anti-TEF anticorps

Antigène: TEF (Thyrotrophic Embryonic Factor (TEF))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Mouton, Boeuf (Vache), Cheval, Cobaye, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TEF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: PVDPQAGPGP GPGRAAGERG LSGSFPLVLK KLMENPPREA RLDKEKGKEK

Homologie: Cow: 93%, Dog: 93%, Goat: 91%, Guinea Pig: 83%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 93%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against TEF. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TEF

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 303 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TEF

Antigène: TEF (Thyrotrophic Embryonic Factor (TEF))

Autre désignation: TEF (TEF Produits)

Sujet: TEF (thyrotroph embryonic factor) is a member of the PAR bZip (proline and acidic amino acid-rich basic leucine zipper) transcription factor family. It accumulates with robust circadian rhythms in tissues with high amplitudes of clock gene expression.Thyrotroph embryonic factor (TEF), a transcription factor, is a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP), VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties.
Alias Symbols: -
Protein Interaction Partner: MRPL28, DBP,
Protein Size: 303

Poids moléculaire: 33 kDa

ID gène: 7008

NCBI Accession: NM_003216, NP_003207

UniProt: Q10587