SAP30 anticorps (Middle Region)
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- Antigène Voir toutes SAP30 Anticorps
- SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Lapin, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SAP30 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- YQLQVNTLRR YKRHFKLPTR PGLNKAQLVE IVGCHFRSIP VNEKDTLTYF
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against SAP30. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human SAP30
- Top Product
- Discover our top product SAP30 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 220 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))
- Autre désignation
- SAP30 (SAP30 Produits)
- Synonymes
- anticorps 30kDa, anticorps Sin3A associated protein 30, anticorps sin3 associated polypeptide, anticorps Sin3A associated protein 30kDa S homeolog, anticorps SAP30, anticorps Sap30, anticorps sap30.S
- Sujet
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Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP30 is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3.
Alias Symbols: -
Protein Interaction Partner: HDAC3, CUL4B, DDB1, HDAC1, SIN3A, UBC, HDAC2, BRMS1L, ING1, ARID4A, SAMSN1, ZNF395, UBASH3B, RBBP7, RBBP4, CHD4, ALL1, TAF6, SMARCA2, SAP25, RBP1, HIST2H2BE, PCBD1, ID3, SAP30BP, HIST2H4A, HBP1, HIST1H2AL, BRMS1, CIR1, HIST3H3, NCOR1, NCOR2, MXD1, YY1, HT
Protein Size: 220 - Poids moléculaire
- 23 kDa
- ID gène
- 8819
- NCBI Accession
- NM_003864, NP_003855
- UniProt
- O75446
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