ZNF259 anticorps (N-Term)
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- Antigène Voir toutes ZNF259 (znf259) Anticorps
- ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ZNF259 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- PPGAAVAPSP APAPPPAPDH LFRPISAEDE EQQPTEIESL CMNCYCNGMT
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against ZNF259. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF259
- Top Product
- Discover our top product znf259 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 459 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))
- Autre désignation
- ZNF259 (znf259 Produits)
- Synonymes
- anticorps RGD1562173, anticorps zpr1, anticorps ZNF259, anticorps ZPR1, anticorps Zfp259, anticorps fc17g10, anticorps si:rp71-56i13.4, anticorps wu:fc17g10, anticorps zgc:56478, anticorps AI303781, anticorps Znf259, anticorps ZPR1 zinc finger, anticorps ZPR1 zinc finger L homeolog, anticorps Zpr1, anticorps ZPR1, anticorps zpr1, anticorps zpr1.L
- Sujet
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ZNF259 may be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus. ZNF259 binds to the EGFR and is released from the receptor after activation.ZNF259 is essential for cell viability and its interaction with eEF-1alpha contributes to normal cellular proliferation.ZNF259 translocates from the cytoplasm to the nucleus after treatment of cells with mitogens. ZNF259 accumulates in the nucleolus of proliferating cells. Loss of ZNF259 caused disruption of nucleolar function, including preribosomal RNA expression. ZNF259 is an essential protein that is required for normal nucleolar function in proliferating cells.
Alias Symbols: ZPR1
Protein Interaction Partner: UBC, P3H1, FKBP10, RPRD1B, OSGEP, PPME1, SZRD1, ARIH1, HSPBP1, ACTR2, ACTR3, ARPC4, UBA2, TOM1L1, OGT, SURF2, PPP1R7, LPP, HSF1, AGFG1, HNRNPF, BAG1, ALAD, MPP3, SRXN1, NUDCD2, UBL7, THOC7, KLC2, UBQLN4, UFM1, UFC1, UBXN1, UHRF1, PHPT1, TES, UBXN7, HYPK,
Protein Size: 459 - Poids moléculaire
- 51 kDa
- ID gène
- 8882
- NCBI Accession
- NM_003904, NP_003895
- UniProt
- O75312
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