ZNF259 anticorps (C-Term)

N° du produit ABIN2780558

Détail du produit anti-ZNF259 anticorps

Antigène: ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Chévre, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF259 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GNSYLQNVYA PEDDPEMKVE RYKRTFDQNE ELGLNDMKTE GYEAGLAPQR

Homologie: Cow: 100%, Dog: 100%, Goat: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ZNF259. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ZNF259

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 459 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ZNF259

Antigène: ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

Autre désignation: ZNF259 (znf259 Produits)

Synonymes: anticorps RGD1562173, anticorps zpr1, anticorps ZNF259, anticorps ZPR1, anticorps Zfp259, anticorps fc17g10, anticorps si:rp71-56i13.4, anticorps wu:fc17g10, anticorps zgc:56478, anticorps AI303781, anticorps Znf259, anticorps ZPR1 zinc finger, anticorps ZPR1 zinc finger L homeolog, anticorps Zpr1, anticorps ZPR1, anticorps zpr1, anticorps zpr1.L

Sujet: ZNF259 may be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus. ZNF259 binds to the EGFR and is released from the receptor after activation.ZNF259 is essential for cell viability and its interaction with eEF-1alpha contributes to normal cellular proliferation.ZNF259 translocates from the cytoplasm to the nucleus after treatment of cells with mitogens. ZNF259 accumulates in the nucleolus of proliferating cells. Loss of ZNF259 caused disruption of nucleolar function, including preribosomal RNA expression. ZNF259 is an essential protein that is required for normal nucleolar function in proliferating cells.
Alias Symbols: ZPR1
Protein Interaction Partner: UBC, P3H1, FKBP10, RPRD1B, OSGEP, PPME1, SZRD1, ARIH1, HSPBP1, ACTR2, ACTR3, ARPC4, UBA2, TOM1L1, OGT, SURF2, PPP1R7, LPP, HSF1, AGFG1, HNRNPF, BAG1, ALAD, MPP3, SRXN1, NUDCD2, UBL7, THOC7, KLC2, UBQLN4, UFM1, UFC1, UBXN1, UHRF1, PHPT1, TES, UBXN7, HYPK,
Protein Size: 459

Poids moléculaire: 51 kDa

ID gène: 8882

NCBI Accession: NM_003904, NP_003895

UniProt: O75312