MED7 anticorps (C-Term)
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- Antigène Voir toutes MED7 Anticorps
- MED7 (Mediator Complex Subunit 7 (MED7))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MED7 est non-conjugé
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Application
- Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
- Séquence
- LASLPDDLPH SEAGMRVKTE PMDADDSNNC TGQNEHQREN SGHRRDQIIE
- Homologie
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against MED7. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product MED7 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 233 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- MED7 (Mediator Complex Subunit 7 (MED7))
- Autre désignation
- MED7 (MED7 Produits)
- Sujet
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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: CRSP33, CRSP9, MGC12284, ARC34
Protein Interaction Partner: HAUS1, CDK8, CDK19, MED13, MED19, MED26, EPAS1, MED6, UBE2I, UL48, SUMO2, UBC, CTDP1, MED10, MED25, MED15, MED14, VDR, SREBF1, RELA, PARP1, ZSCAN1, TRIM15, RHOXF2, PCBD2, MED31, TRIM29, RBFOX2, IKBKG, LZTR1, PML, MED9, MED8, HGS, MED1, HNF4A, ESR2, ESR1,
Protein Size: 233 - Poids moléculaire
- 27 kDa
- ID gène
- 9443
- NCBI Accession
- NM_004270, NP_004261
- UniProt
- O43513
- Pathways
- Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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