ONECUT1 anticorps (Middle Region)

N° du produit ABIN2780599

Détail du produit anti-ONECUT1 anticorps

Antigène: ONECUT1 (One Cut Homeobox 1 (ONECUT1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Porc, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ONECUT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: ITISQQLGLE LSTVSNFFMN ARRRSLDKWQ DEGSSNSGNS SSSSSTCTKA

Homologie: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against ONECUT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ONECUT1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 465 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ONECUT1 (ABIN2780599)

Yuan, Wang, Hu, Tang, Shi, Guo, Song: "Hepatocyte nuclear factor 6 suppresses the migration and invasive growth of lung cancer cells through p53 and the inhibition of epithelial-mesenchymal transition." dans: The Journal of biological chemistry, Vol. 288, Issue 43, pp. 31206-16, (2013) (PubMed).

Huang, Mei, Yu, Zhang, Han, Jiang, Zhou: "Distribution of the interstitial Cajal-like cells in the gallbladder and extrahepatic biliary duct of the guinea-pig." dans: Acta histochemica, Vol. 111, Issue 2, pp. 157-65, (2009) (PubMed).

Détails sur ONECUT1

Antigène: ONECUT1 (One Cut Homeobox 1 (ONECUT1))

Autre désignation: ONECUT1 (ONECUT1 Produits)

Synonymes: anticorps D9Ertd423e, anticorps HNF-6, anticorps Hfh12, anticorps Hnf6, anticorps Hnf6b, anticorps OC-1, anticorps Oc1, anticorps onecut, anticorps onecut1, anticorps id:ibd5005, anticorps HNF6, anticorps HNF6A, anticorps HNF-6a, anticorps oc1, anticorps onecut1l, anticorps zgc:65904, anticorps zgc:77450, anticorps one cut domain, family member 1, anticorps one cut homeobox 1, anticorps one cut domain, family member, like, anticorps Onecut1, anticorps onecutl, anticorps ONECUT1, anticorps onecut1

Sujet: ONECUT1 belongs to the CUT homeobox family. It contains 1 CUT DNA-binding domain and 1 homeobox DNA-binding domain. It is a transcriptional activator. ONECUT1 binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.
Alias Symbols: HNF-6, HNF6, HNF6A
Protein Interaction Partner: NR0B2, KAT2B, FOXA2, CREBBP, NR3C1, FOXA1,
Protein Size: 465

Poids moléculaire: 51 kDa

ID gène: 3175

NCBI Accession: NM_004498, NP_004489

UniProt: Q9UBC0