TCEAL1 anticorps (Middle Region)

N° du produit ABIN2780618

Détail du produit anti-TCEAL1 anticorps

Antigène: TCEAL1 (Transcription Elongation Factor A (SII)-Like 1 (TCEAL1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCEAL1 est non-conjugé

Application: Western Blotting (WB)

Séquence: RPQFRGDIHG RNLSNEEMIQ AADELEEMKR VRNKLMIMHW KAKRSRPYPI

Homologie: Cow: 85%, Dog: 85%, Horse: 85%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TCEAL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TCEAL1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 159 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TCEAL1 (ABIN2780618)

Klos, Wyszomierski, Sun, Tan, Zhou, Li, Yang, Yin, Hittelman, Yu: "ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells." dans: Cancer research, Vol. 66, Issue 4, pp. 2028-37, (2006) (PubMed).

Détails sur TCEAL1

Antigène: TCEAL1 (Transcription Elongation Factor A (SII)-Like 1 (TCEAL1))

Autre désignation: TCEAL1 (TCEAL1 Produits)

Synonymes: anticorps SIIR, anticorps p21, anticorps pp21, anticorps 0610011M09Rik, anticorps BC011290, anticorps P21, anticorps transcription elongation factor A like 1, anticorps transcription elongation factor A (SII)-like 1, anticorps TCEAL1, anticorps Tceal1

Sujet: TCEAL1 is a member of the transcription elongation factor A (SII)-like (TCEAL) protein family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. TCEAL1 is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform.
Alias Symbols: SIIR, p21, pp21
Protein Interaction Partner: MAPK14, DYRK1B, UBC, HOXB6, USP11, TCEAL2, TCEAL4, FEM1C, PPP2R2D, KDM3A, FEM1A, TIPIN, PDCD5, GMPS, CUL2, USP7, TCEB1, RFC1, HSPA4L, SSR3, PPP2R2A,
Protein Size: 159

Poids moléculaire: 19 kDa

ID gène: 9338

NCBI Accession: NM_004780, NP_004771

UniProt: Q15170