CIAO1 anticorps (C-Term)

N° du produit ABIN2780621

Détail du produit anti-CIAO1 anticorps

Antigène: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIAO1 est non-conjugé

Application: Western Blotting (WB)

Séquence: HSRTIYDIAW CQLTGALATA CGDDAIRVFQ EDPNSDPQQP TFSLTAHLHQ

Homologie: Cow: 86%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against WDR39. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human WDR39

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 339 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CIAO1

Antigène: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Autre désignation: WDR39 (CIAO1 Produits)

Synonymes: anticorps CG12797, anticorps Dmel\\CG12797, anticorps DDBDRAFT_0190506, anticorps DDBDRAFT_0266672, anticorps DDB_0190506, anticorps DDB_0266672, anticorps CIA1, anticorps WDR39, anticorps AW210570, anticorps Wdr39, anticorps wdr39, anticorps zgc:55911, anticorps zgc:77394, anticorps CG12797 gene product from transcript CG12797-RA, anticorps WD40 protein Ciao1, anticorps CIAO1, anticorps WD40 repeat-containing protein, anticorps cytosolic iron-sulfur assembly component 1, anticorps cytosolic iron-sulfur protein assembly 1, anticorps Ciao1, anticorps cgd1_2230, anticorps CC1G_05316, anticorps ciao1, anticorps CIAO1

Sujet: WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.
Alias Symbols: CIA1, WDR39
Protein Interaction Partner: FAM96B, SF1, MEOX1, FAM96A, MMS19, FMNL2, TOE1, DPP9, FMNL3, CTU1, PPIL4, MAK16, WDR75, NSRP1, EEPD1, WDR61, CDC73, UPF3B, NARFL, YAE1D1, TYW1, ELP2, ELP3, UCKL1, CDKAL1, DPP8, ELP6, PAF1, PLEKHA5, PHAX, RTEL1, ELP4, POLA2, ELP5, WDR43, ERP29, GLRX3, CTR9
Protein Size: 339

Poids moléculaire: 38 kDa

ID gène: 9391

NCBI Accession: NM_004804, NP_004795

UniProt: O76071