MECOM anticorps (N-Term)
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- Antigène Voir toutes MECOM Anticorps
- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MECOM est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MRSKGRARKL ATNNECVYGN YPEIPLEEMP DADGVASTPS LNIQEPCSPA
- Homologie
- Human: 100%, Mouse: 93%, Zebrafish: 77%
- Attributs du produit
- This is a rabbit polyclonal antibody against MDS1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human MDS1
- Top Product
- Discover our top product MECOM Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 169 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
- Autre désignation
- MDS1 (MECOM Produits)
- Synonymes
- anticorps AML1-EVI-1, anticorps EVI1, anticorps MDS1, anticorps MDS1-EVI1, anticorps PRDM3, anticorps D630039M04Rik, anticorps Evi-1, anticorps Evi1, anticorps Jbo, anticorps Mds, anticorps Mds1, anticorps Mds1-Evi1, anticorps Prdm3, anticorps Znfpr1b1, anticorps evi1, anticorps im:7140716, anticorps prdm3, anticorps evi-1, anticorps mecom, anticorps mecom-a, anticorps mecom-b, anticorps xEvi-1, anticorps evi1-B, anticorps MDS1 and EVI1 complex locus, anticorps MDS1 and EVI1 complex locus L homeolog, anticorps MDS1 and EVI1 complex locus S homeolog, anticorps MECOM, anticorps Mecom, anticorps mecom, anticorps mecom.L, anticorps mecom.S
- Sujet
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MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped. MDS1 has been identified as a single gene as well as a previously unreported exon(s) of EVI1. MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame. In cells with translocation t (3,21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1. EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.
Alias Symbols: PRDM3, MDS1-EVI1
Protein Size: 169 - Poids moléculaire
- 19 kDa
- ID gène
- 4197
- NCBI Accession
- NM_004991, NP_004982
- UniProt
- Q13465
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