SAP18 anticorps (N-Term)

N° du produit ABIN2780718

Détail du produit anti-SAP18 anticorps

Antigène: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAP18 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: EIKKEPEKPI DREKTCPLLL RVFTTNNGRH HRMDEFSRGN VPSSELQIYT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SAP18. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SAP18

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 153 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SAP18

Antigène: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Autre désignation: SAP18 (SAP18 Produits)

Synonymes: anticorps zgc:73118, anticorps C530046K05Rik, anticorps D11Ertd539e, anticorps EMegR4, anticorps Sinbp1, anticorps 2HOR0202, anticorps SAP18P, anticorps Sin3A-associated protein, anticorps Sin3-associated polypeptide 18, anticorps Sin3A associated protein 18, anticorps Sin3A associated protein 18kDa S homeolog, anticorps sap18, anticorps Sap18, anticorps sap18.S, anticorps SAP18

Sujet: Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP18 is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.
Alias Symbols: SAP18P, 2HOR0202
Protein Interaction Partner: INCA1, RBM39, UBC, RNF2, SUZ12, BMI1, CSNK2A2, MAGOH, EIF4A3, VCP, NFIA, SEPT2, MYO1C, IK, HNRNPU, HNRNPC, GTF3C1, SEPT7, CDC5L, U2AF1, SNRPD2, SMARCC2, SMARCB1, SRSF7, SRSF5, SRSF3, SRSF1, SAFB, S100A9, PSAP, NHP2L1, TPR, TFPI, SURF4, SSRP1, SSR3, LOC255
Protein Size: 153

Poids moléculaire: 18 kDa

ID gène: 10284

NCBI Accession: NM_005870, NP_005861

UniProt: O00422