NRF2 anticorps (C-Term)
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- Antigène Voir toutes NRF2 (NFE2L2) Anticorps
- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NRF2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- KEKGENDKSL HLLKKQLSTL YLEVFSMLRD EDGKPYSPSE YSLQQTRDGN
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against NFE2L2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human NFE2L2
- Top Product
- Discover our top product NFE2L2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 605 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
- Autre désignation
- NFE2L2 (NFE2L2 Produits)
- Synonymes
- anticorps Nrf2, anticorps nfe2l2, anticorps wu:fc15g09, anticorps wu:fj67e03, anticorps NF-E2R2, anticorps NRF2, anticorps AI194320, anticorps nuclear factor, erythroid 2-like 2a, anticorps nuclear factor, erythroid 2 like 2 S homeolog, anticorps nuclear factor, erythroid 2 like 2, anticorps nuclear factor, erythroid derived 2, like 2, anticorps nuclear factor, erythroid 2-like 2, anticorps nfe2l2a, anticorps nfe2l2.S, anticorps NFE2L2, anticorps Nfe2l2
- Sujet
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NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other. NFE2L2 may be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995).[supplied by OMIM].
Alias Symbols: NRF2
Protein Interaction Partner: BACH1, HDAC3, WAC, FBXW11, KEAP1, TNNT1, MAPK7, HDAC2, HDAC1, MAFF, MAFG, MAFK, MAP2K2, MAP2K1, MAPK9, MAPK8, AKT1, UBC, NQO1, BRCA1, AHR, CREB3, NFE2L3, ENC1, SIAH2, NFE2, ATF4, Pparg, SUMO1, SUMO2, RNF4, BPTF, RBMX, KPNA3, SUMO3, MYC, DYT10, Ube2e1, PGA
Protein Size: 605 - Poids moléculaire
- 68 kDa
- ID gène
- 4780
- NCBI Accession
- NM_006164, NP_006155
- UniProt
- Q16236
- Pathways
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
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